Neurosurgical Randomized Controlled Trials—Distance Travelled

The road less travelled

In the ever more competitive arena of biological research, there is a widespread perception that, if you haven’t got a firm foothold on the ladder by your late twenties, you’ll never make it. It’s tempting to believe this. Indeed, working at Cold Spring Harbor’s Watson School of Biological Sciences brings me into daily contact with biologists of all ages and stages, who are nothing if not highl...

Blindness in Randomized Controlled Trials

In combination with randomization, blinding or masking is an important factor in randomized controlled trials (RCTs), particularly in trials that assess therapeutic effects. Here an attempt is made to explain blindness and why it is important. In clinical trials, blinding is defined as the condition imposed on a study in which study participants, health care providers and assessors collecting o...

The road less travelled.

660 British Journal of General Practice, December 2012 I think our satnav must be agnostic. It certainly didn’t seem to recognise the existence of a church where a wedding we were due at was about to take place. It took a while to realise that the calm soothing tones coming from our dashboard were leading us nowhere and we had to try and find another way to get to the church on time. Smartphone...

Controlled Study of Correlation of Biomechanical Profile of Hemiparetic Patients with Distance Travelled in Six Minutes

The six-minute walking test (6MWT) is used to assess exercise tolerance that is associated with motor function of the lower limbs in hemiparetic patients. It is suggested that, for post-stroke subjects, performance in the 6MWT may be limited by biomechanical and cardiovascular factors. Our aim is to determine the correlation between the six-minute walk distance (6MWD) and the biomechanical prof...

A Comparative Evaluation of Risk Factors and Various Antibiotic Regimens in Postoperative Neurosurgical Infections: A Prospective Randomized Controlled Study